Best Friends: Star and Chica

Aside from being best friends with their "pet humans," Chica the Chicken and Star, the two faces of the "main ten" of the gang (them, Nina, Miles, the House Band, Bean, Noodle, and JB), share a sister and brother-like relationship. It all started in 2007, shortly after The Sunny Side Up Show made its debut - Star was sad because of a rough day he had, so Chica offered to cheer him up, and as you can tell, they both had fun. They became friends that day, and their friendship grew and grew as time went by and now they're best friends like siblings (sisters and brothers). These two do what best friends do - they never fight, but if they do, they always make up.